CoPilot AI-Assisted Car Shopping

 New Search
 Save
 Sort
 Share

Used 2021 Ram 2500 for Sale in Greenville, SC

2500s for Sale at Dealers

Filters
Price
Year
Mileage
Trim
2021 Ram 2500 Big Horn 4WD photo
2021 Ram 2500 Big Horn 4WD • Greenville, SC
Black • 6.4L V8 Engine
$32,995 • 115.9k miles
•••

Not Ranked

CoPilot AI: It’s a “D” Buy

  • Includes $436 Premium Upgrades
  • Dealer Rating - 4.4 stars
More details
2020 Ram 2500 Power Wagon 4WD photo
New Find
2020 Ram 2500 Power Wagon 4WD • Easley, SC
Blue • 6.4L V8 Engine
$38,753 • 81.4k miles
•••

Not Ranked

CoPilot AI: It’s a “C” Buy

  • Includes $375 Premium Upgrades
  • Average Mileage
  • Dealer Rating - 4.7 stars
More details
2021 Ram 2500 Tradesman 4WD photo
Price Drop
New Find
2021 Ram 2500 Tradesman 4WD • Travelers Rest, SC
Black • 6.4L V8 Engine
$28,172 • 99.7k miles
•••

Not Ranked

CoPilot AI: It’s an “A+” Buy

  • $311 Price Drop
  • Great Price - $2,935 Below Market
  • Includes $4,008 Premium Upgrades
More details
2022 Ram 2500 Tradesman 4WD photo
2022 Ram 2500 Tradesman 4WD • Travelers Rest, SC
White • 6.4L V8 Engine
$28,038 • 112.1k miles
•••

Not Ranked

CoPilot AI: It’s a “B+” Buy

  • Fair Price - $663 Below Market
  • Includes $2,062 Premium Upgrades
  • CARFAX: One Owner
More details
2021 Ram 2500 Big Horn 4WD photo
New Find
2021 Ram 2500 Big Horn 4WD • Greer, SC
Gray • 6.7L I6 Engine
$47,149 • 41.9k miles
•••

Not Ranked

CoPilot AI: It’s an “A+” Buy

  • Great Price - $3,714 Below Market
  • Includes $15,806 Premium Upgrades
  • CARFAX: One Owner
More details
2021 Ram 2500 Big Horn 4WD photo
2021 Ram 2500 Big Horn 4WD • Lyman, SC
Silver • 6.4L V8 Engine
$35,045 • 93.4k miles
•••

Not Ranked

CoPilot AI: It’s a “D” Buy

  • Motivation to Negotiate - Very High
  • Dealer Rating - 4.5 stars
More details
2021 Ram 2500 Big Horn 4WD photo
New Find
2021 Ram 2500 Big Horn 4WD • Spartanburg, SC
Gray • 6.7L I6 Engine
$36,999 • 90k miles
•••

Not Ranked

CoPilot AI: It’s a “B+” Buy

  • Good Price - $1,321 Below Market
  • Includes $7,526 Premium Upgrades
More details
2022 Ram 2500 Power Wagon 4WD photo
Price Drop
2022 Ram 2500 Power Wagon 4WD • Spartanburg, SC
Red • 6.4L V8 Engine
$47,399 • 66.4k miles • Certified
•••

Not Ranked

CoPilot AI: It’s an “A-” Buy

  • Fair Price - $463 Below Market
  • Includes $7,256 Premium Upgrades
  • CARFAX: One Owner
More details
2022 Ram 2500 Tradesman 4WD photo
2022 Ram 2500 Tradesman 4WD • Spartanburg, SC
White • 6.4L V8 Engine
$32,500 • 92.2k miles
•••

Not Ranked

CoPilot AI: It’s a “B-” Buy

  • Includes $2,326 Premium Upgrades
  • Motivation to Negotiate - Very High
  • Dealer Rating - 4.6 stars
More details
2022 Ram 2500 Limited 4WD photo
2022 Ram 2500 Limited 4WD • Anderson, SC
White • 6.7L I6 Engine
$60,450 • 87k miles
•••

Not Ranked

CoPilot AI: It’s a “C-” Buy

  • Includes $8,033 Premium Upgrades
  • Motivation to Negotiate - Increasing
  • Dealer Rating - 4.7 stars
More details
2022 Ram 2500 Big Horn 4WD photo
2022 Ram 2500 Big Horn 4WD • Anderson, SC
Gray • 6.7L I6 Engine
$42,462 • 79.1k miles
•••

Not Ranked

CoPilot AI: It’s an “A” Buy

  • Good Price - $1,741 Below Market
  • Includes $10,345 Premium Upgrades
  • Motivation to Negotiate - Increasing
More details
2021 Ram 2500 Tradesman 4WD photo
2021 Ram 2500 Tradesman 4WD • Anderson, SC
White • 6.7L I6 Engine
$33,999 • 111.3k miles
•••

Not Ranked

CoPilot AI: It’s an “A-” Buy

  • Fair Price - $690 Above Market
  • Includes $7,681 Premium Upgrades
  • Dealer Rating - 4.7 stars
More details
2022 Ram 2500 Tradesman 4WD photo
2022 Ram 2500 Tradesman 4WD • Anderson, SC
White • 6.4L V8 Engine
$33,900 • 102.8k miles
•••

Not Ranked

CoPilot AI: It’s a “D+” Buy

  • Includes $2,333 Premium Upgrades
  • CARFAX: One Owner
  • Motivation to Negotiate - Increasing
More details
2021 Ram 2500 Laramie 4WD photo
Price Drop
2021 Ram 2500 Laramie 4WD • Hendersonville, NC
Gray • 6.7L I6 Engine
$64,743 • 38.8k miles
•••

Not Ranked

CoPilot AI: It’s a “C” Buy

  • $33 Price Drop
  • Includes $12,602 Premium Upgrades
  • Motivation to Negotiate - Very High
More details
2022 Ram 2500 Limited 4WD photo
New Find
2022 Ram 2500 Limited 4WD • Hendersonville, NC
White • 6.7L I6 Engine
$58,000 • 58.3k miles
•••

Not Ranked

CoPilot AI: It’s an “A-” Buy

  • Fair Price - $567 Above Market
  • Includes $8,416 Premium Upgrades
  • CARFAX: One Owner
More details
2021 Ram 2500 Laramie 4WD photo
2021 Ram 2500 Laramie 4WD • Gaffney, SC
Red • 6.7L I6 Engine
$43,890 • 104.2k miles
•••

Not Ranked

CoPilot AI: It’s an “A-” Buy

  • Fair Price - $325 Above Market
  • Includes $9,136 Premium Upgrades
  • CARFAX: One Owner
More details
2021 Ram 2500 Power Wagon 4WD photo
Price Drop
New Find
2021 Ram 2500 Power Wagon 4WD • Forest City, NC
Black • 6.4L V8 Engine
$45,598 • 49.9k miles
•••

Not Ranked

CoPilot AI: It’s a “B” Buy

  • $387 Price Drop
  • Includes $3,625 Premium Upgrades
  • CARFAX: One Owner
More details
2022 Ram 2500 Tradesman 4WD photo
Price Drop
2022 Ram 2500 Tradesman 4WD • Asheville, NC
Red • 6.7L I6 Engine
$36,395 • 56.5k miles
•••

Not Ranked

CoPilot AI: It’s an “A” Buy

  • $522 Price Drop
  • Good Price - $2,214 Below Market
  • Includes $9,628 Premium Upgrades
More details
2022 Ram 2500 Big Horn 4WD photo
2022 Ram 2500 Big Horn 4WD • Asheville, NC
Silver • 6.7L I6 Engine
$39,950 • 90.3k miles
•••

Not Ranked

CoPilot AI: It’s a “C-” Buy

  • Includes $5,717 Premium Upgrades
  • Motivation to Negotiate - Very High
  • Dealer Rating - 4.1 stars
More details
2021 Ram 2500 Laramie 4WD photo
2021 Ram 2500 Laramie 4WD • Asheville, NC
White • 6.7L I6 Engine
$39,335 • 110.5k miles • Certified
•••

Not Ranked

CoPilot AI: It’s an “A+” Buy

  • Great Price - $8,871 Below Market
  • Includes $10,169 Premium Upgrades
  • Dealer Rating - 4.5 stars
More details
2022 Ram 2500 Limited 4WD photo
Price Drop
2022 Ram 2500 Limited 4WD • Marion, NC
Black • 6.7L I6 Engine
$59,699 • 41.9k miles • Certified
•••

Not Ranked

CoPilot AI: It’s an “A” Buy

  • $100 Price Drop
  • Fair Price - $338 Below Market
  • Includes $10,401 Premium Upgrades
More details
2021 Ram 2500 Power Wagon 4WD photo
Price Drop
New Find
2021 Ram 2500 Power Wagon 4WD • Franklin, NC
Black • 6.4L V8 Engine
$44,400 • 92.6k miles
•••

Not Ranked

CoPilot AI: It’s a “C-” Buy

  • $100 Price Drop
  • Includes $2,452 Premium Upgrades
  • Dealer Rating - 4.5 stars
More details
2021 Ram 2500 Limited 4WD photo
2021 Ram 2500 Limited 4WD • Morganton, NC
White • 6.7L I6 Engine
$56,787 • 81k miles
•••

Not Ranked

CoPilot AI: It’s a “B-” Buy

  • Includes $10,477 Premium Upgrades
  • Motivation to Negotiate - High
  • Dealer Rating - 4.3 stars
More details
2020 Ram 2500 Big Horn 4WD photo
New Find
2020 Ram 2500 Big Horn 4WD • Morganton, NC
6.4L V8 Engine
$37,899 • 86.5k miles
•••

Not Ranked

CoPilot AI: It’s a “D” Buy

  • Average Mileage
  • Dealer Rating - 4.3 stars
More details
2022 Ram 2500 Tradesman 4WD photo
Price Drop
2022 Ram 2500 Tradesman 4WD • Gastonia, NC
Red • 6.7L I6 Engine
$34,034 • 94k miles
•••

Not Ranked

CoPilot AI: It’s a “B-” Buy

  • $50 Price Drop
  • Includes $7,766 Premium Upgrades
  • CARFAX: One Owner
More details
1-25 of 79 results

2021 Ram 2500

Three-Quarter-Ton Truck
Seats
5
NHTSA Rating Summary
Copilot Rating
Dimensions

© 2026 CoPilot. All Rights Reserved.